| 製品名 |
von Hippel-Lindau (VHL) |
MDM2 |
Cereblon |
IAP |
KLHDC2 |
Fbxo3 |
RNF4 |
DCAF11 |
DCAF1 |
UHRF1 |
TRIM21 |
NEURL1B |
KLHL41 |
純度 |
| Pomalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.96% |
| Lenalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.94% |
| CC-885 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.26% |
| E3 ligase Ligand 79 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.07% |
| (S,R,S)-AHPC-Me-C8-NHS ester |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.89% |
| Iberdomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.54% |
| Eragidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.93% |
| Oridonin |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.89% |
| PT-179 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.91% |
| VH-298 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.78% |
| VH032 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.43% |
| (S,R,S)-AHPC |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.13% |
| Golcadomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.04% |
| E3 ligase Ligand 32 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.95% |
| (S,R,S)-AHPC monohydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.83% |
| (S,R,S)-AHPC-Me |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.96% |
| BMS-986397 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.76% |
| (S,R,S)-AHPC-Me hydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.95% |
| Lenalidomide hemihydrate |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.98% |
| E3 ligase Ligand 63 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.80% |
| CRBN ligand-547 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.82% |
| VHL-IN-1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.84% |
| CC-3060 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.7% |
| ALV2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.05% |
| 5-Norbornene-2-methylamine |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.91% |
| ALV1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.62% |
| CRBN ligand-109 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.62% |
| BODIPY FL thalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.18% |
| CRBN ligand-881 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.30% |
| BC-1215 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.94% |
| CCW16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.73% |
| CRBN ligand-880 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.96% |
| Lenalidomide-Br |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.86% |
| VH032-cyclopropane-F |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.92% |
| (S)-Thalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.52% |
| CRBN ligand-397 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.77% |
| PLX-4545 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| VH 101, acid |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.82% |
| MDM2 ligand 5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.02% |
| Lenalidomide-I |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.84% |
| E3 ligase Ligand 64 |
|
|
|
|
|
|
|
|
|
|
|
|
|
≥98.0% |
| DCAF1 binder 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.12% |
| (S,S,S)-AHPC hydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.16% |
| Lenalidomide (Standard) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 5,6-Difluoro-desamino lenalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.94% |
| NCT02 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.14% |
| (S,R,S)-AHPC-propargyl |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.46% |
| Lenalidomide-OH |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.48% |
| (S,R,S)-AHPC-Boc |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| NV03 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.77% |
| MRT-3486 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.62% |
| Thalidomide-5-Br |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.92% |
| OICR-8268 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.23% |
| Thalidomide (Standard) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-13 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 5-Aminothalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.69% |
| (S,R,S)-AHPC-Me-NHBoc |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.26% |
| 5-Br-6-F-Desamino lenalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Desamino lenalidomide-6-COOH |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.45% |
| N-Me-Thalidomide 4-fluoride |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.41% |
| E3 ligase Ligand PG |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.94% |
| PD 4'-oxyacetic acid |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.69% |
| Hydrouracil-3-Ph-COOH |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.91% |
| (S,R,S)-AHPC-Me dihydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.84% |
| VL285 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.34% |
| Nutlin carboxylic acid |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.63% |
| KB02-COOH |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.88% |
| Desamino lenalidomide-5-F |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 2-Methoxyphenyl dihydrouracil |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.0% |
| Desamino lenalidomide-CH2NH2 hydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Lenalidomide 5'-piperazine hydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.92% |
| Pomalidomide-5-OH |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.46% |
| CRBN ligand-224 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.70% |
| CRBN ligand-394 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.77% |
| CRBN ligand-798 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| TD-106 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.81% |
| Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.57% |
| Desamino lenalidomide-6-OH |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.36% |
| Desamino lenalidomide-pinacolborane |
|
|
|
|
|
|
|
|
|
|
|
|
|
≥98.0% |
| CRBN ligand-734 |
|
|
|
|
|
|
|
|
|
|
|
|
|
≥98.0% |
| CC-17369 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.68% |
| VHL Ligand 14 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.93% |
| VHL Ligand 8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.04% |
| AR antagonist 1 hydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.53% |
| Lenalidomide-F |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.89% |
| CRBN ligand-660 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.31% |
| Desamino lenalidomide-7-OH |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.11% |
| BWA-522 intermediate-1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.27% |
| 3-(4-Bromo-2-chlorophenyl)piperidine-2,6-dione |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.92% |
| Pomalidomide (Standard) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| IPS-06061 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-11 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.94% |
| Thalidomide-piperazine hydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.27% |
| GNE7599 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.19% |
| (R,S,S)-VH032 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.99% |
| E3 ligase Ligand 56 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.88% |
| Pomalidomide-6-OH |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.81% |
| 2-(2,6-Dioxopiperidin-3-yl)phthalimidine |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.08% |
| N-Methylated pomalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (R)-Thalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.80% |
| CRBN ligand-838 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| VH 101, thiol |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.66% |
| CRBN ligand-395 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 4-Chloro-3-(2,4-dioxo-1,3-diazinan-1-yl)benzoic acid |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.28% |
| cIAP1 ligand 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.90% |
| cis VH-298 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.96% |
| Cereblon inhibitor 2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.09% |
| E3 ligase Ligand 51 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.42% |
| Pomalidomide-d3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.0% |
| E3 ligase Ligand 23 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.39% |
| CRBN modulator-1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.00% |
| Glutarimide-(1-oxoisoindoline-5-carbaldehyde) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-774 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-788 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.89% |
| Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.08% |
| AR antagonist 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.03% |
| Desamino lenalidomide-5-COOH |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.01% |
| CRBN ligand-661 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Thalidomide-O-amido-PEG2-Mal |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S)-Thalidomide 4-fluoride |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-47 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.93% |
| Desamino lenalidomide-NO2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.76% |
| 3-(4-Bromo-2-fluorophenyl)piperidine-2,6-dione |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.55% |
| CRBN ligand-617 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Pomalidomide-d4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 18 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.22% |
| Thalidomide-(2)piperidine |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.42% |
| Thalidomide-pyrrolidine hydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.0% |
| Cereblon inhibitor 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.19% |
| Thalidomide-d4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.71% |
| Lenalidomide-d5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.32% |
| E3 ligase Ligand 8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.32% |
| Thalidomide-5-methyl |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.87% |
| CRBN ligand-9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.0% |
| VH032 thiol |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| SJF-0661 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.2% |
| N-Methylthalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| VL285 Phenol |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.56% |
| Pomalidomide-15N,13C5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-789 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (R)-Desamino lenalidomide-5-Br |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.69% |
| CRBN ligand-206 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 5-Fluoro-lenalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Desamino lenalidomide-6-propyne |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-891 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Desamino lenalidomide-COOH |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.58% |
| Desamino lenalidomide-6-Br-5-F |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-884 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-704 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Desamino lenalidomide-alkynes |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-733 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Desamino lenalidomide-7-F |
|
|
|
|
|
|
|
|
|
|
|
|
|
≥98.0% |
| C5 Lenalidomide-CH3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Desamino lenalidomide-4-C-COOH |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Desamino lenalidomide-5-CO |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-883 |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.71% |
| CRBN ligand-618 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-882 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| N-Methyl-desamino lenalidomide-NH2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-225 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-761 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Hydrouracil-4-fluorobenzoate |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-430 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-902 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Desamino lenalidomide-5-C-COOH |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Lenalidomide hydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S,R,S)-AHPC TFA |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Thalidomide-cyanine 5 |
|
|
Cereblon-DDB1, Kd: 121.6 nM
|
|
|
|
|
|
|
|
|
|
|
|
| VHL Ligand 39 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Aster-A Ligand-3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| KLHDC2 ligand 3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 26 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 42 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| SJ1008066 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 22 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Pomalidomide-5-O-CH3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 10 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| DA-PROTAC |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (4R,5S)-Nutlin carboxylic acid |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PROTAC CRBN ligand-2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| HOXB7 8–25 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 14 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 48 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| LCK degrader-3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 38 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| DDB1 ligand-1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-17 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Lenalidomide-13C5,15N |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-905 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (rel)-Nutlin carboxylic acid |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Deoxy-thalidomide-OMe |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 57 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S,R,R)-VH032 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 37 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 36 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-192 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S,R,S)-AHPC-Ala |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| KLHDC2 ligand 4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-896 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Pomalidomide-piperazine |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Bestatin-amido-Me |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 31 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Cyclopropane-(S,R,S)-AHPC |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 44 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 27 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| VH032 analogue-2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| EN10 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 25 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S)-Deoxy-thalidomide-Br |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Acepromazine-OTs |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 21 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Lenalidomide 5'-piperazine |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| VH032-CH2-Boc |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S)-Deoxy-thalidomide |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| MV-1-NH-Me |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 13 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (R)-Pomalidomide-pyrrolidine |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S,R,S,R)-AHPC-Me |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Thalidomide-azetidine-CHO |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| MY-11B |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Ru-Poma |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 45 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| VH032 analogue-1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| BCL-xL/BCL-2 ligand 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| IAP ligand 10 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| HL389 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (3S)Lenalidomide-5-Br |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.61% |
| VH032-NH-CO-CH2-NHBoc |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-191 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-898 |
|
|
Cereblon, Kd: 216 nM
Cereblon, IC50: 183 nM
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 54 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-893 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-901 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| DCAF11 ligand 2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-903 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-895 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 34 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Me-SJ46411 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| MEL23 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 75 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| OICR-8268-acrylic acid |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| RR-11055 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S)-(S,R,S,R)-AHPC-Me-N3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| N-Boc-SBP-0636457-OH |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ubiquitin ligase binder-1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Thalidomide-methylpyrrolidine |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| ALAPYIP |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S,R,S)-AHPC-Ac |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Pomalidomide-d5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| DCAF1 ligand 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 33 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Cereblon ligand-5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S,R,S)-AHPC-O-CF3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| (S,R,S)-AHPC dihydrochloride |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 35 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Pomalidomide 7'OMe |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-190 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| SJ46411-Br |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 43 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 7 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 41 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| AS1411-C4-VH032 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 76 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| VHL-SF2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| cIAP1 ligand 2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| SMARCA2 ligand-14 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| L321 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| cIAP1 ligand 4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Pomalidomide-6-O-CH3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| E3 ligase Ligand 29 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-894 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| NEURL1B-IN-1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| VHL Ligand intermediate-2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Thalidomide-C4-N2-C2-N3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-786 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-181 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-200 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-625 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-775 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-363 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-557 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-782 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-868 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-202 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-436 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-694 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-448 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-333 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-253 |
|
|
|
|
|
|
|
|
|
|
|
|
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| CRBN ligand-332 |
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| CRBN ligand-348 |
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| CRBN ligand-840 |
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| CRBN ligand-244 |
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| CRBN ligand-781 |
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| CRBN ligand-211 |
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| Desamino lenalidomide-Bpin |
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| Desamino lenalidomide[3,4-g]piperidine |
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| CRBN ligand-351 |
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| CRBN ligand-504 |
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| CRBN ligand-604 |
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| CRBN ligand-495 |
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| CRBN ligand-204 |
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| CRBN ligand-714 |
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| CRBN ligand-515 |
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| CRBN ligand-284 |
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| CRBN ligand-702 |
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| CRBN ligand-652 |
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| CRBN ligand-645 |
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| CRBN ligand-746 |
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| CRBN ligand-726 |
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| CRBN ligand-447 |
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| CRBN ligand-328 |
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| Hydrouracil-3-PhOH |
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| CRBN ligand-730 |
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| CRBN ligand-744 |
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| CRBN ligand-675 |
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| CRBN ligand-512 |
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| CRBN ligand-519 |
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| CRBN ligand-474 |
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| CRBN ligand-600 |
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| (S,R,S)-AHPC-PEG2-SH |
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| CRBN ligand-538 |
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| CRBN ligand-590 |
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| CRBN ligand-592 |
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| CRBN ligand-377 |
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| CRBN ligand-428 |
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| CRBN ligand-498 |
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| CRBN ligand-477 |
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| CRBN ligand-267 |
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| CRBN ligand-423 |
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| CRBN ligand-220 |
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| CRBN ligand-256 |
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| CRBN ligand-728 |
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| CRBN ligand-544 |
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| CRBN ligand-579 |
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| CRBN ligand-554 |
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| CRBN ligand-325 |
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| CRBN ligand-556 |
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| CRBN ligand-680 |
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| CRBN ligand-690 |
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| CRBN ligand-273 |
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| CRBN ligand-289 |
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| CRBN ligand-836 |
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| CRBN ligand-500 |
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| CRBN ligand-804 |
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| CRBN ligand-453 |
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| CRBN ligand-369 |
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| CRBN ligand-867 |
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| CRBN ligand-382 |
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| CRBN ligand-208 |
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| CRBN ligand-753 |
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| CRBN ligand-686 |
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| CRBN ligand-478 |
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| CRBN ligand-228 |
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| CRBN ligand-874 |
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| CRBN ligand-620 |
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| CRBN ligand-304 |
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| CRBN ligand-376 |
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| CRBN ligand-855 |
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| CRBN ligand-552 |
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| CRBN ligand-864 |
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| CRBN ligand-511 |
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| CRBN ligand-359 |
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| CRBN ligand-111 |
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| VHL Ligand 35 |
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| CRBN ligand-826 |
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| CRBN ligand-366 |
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| CRBN ligand-723 |
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| CRBN ligand-650 |
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| CRBN ligand-458 |
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| CRBN ligand-522 |
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| Desamino lenalidomide-6-C-COOH |
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| CRBN ligand-76 |
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| CRBN ligand-807 |
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| CRBN ligand-148 |
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| CRBN ligand-606 |
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| CRBN ligand-298 |
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| CRBN ligand-371 |
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| CRBN ligand-570 |
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| CRBN ligand-14 |
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| CRBN ligand-803 |
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| CRBN ligand-389 |
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| (R,R,R)-AHPC hydrochloride |
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| CRBN ligand-735 |
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| (S,R,R)-VH032 hydrochloride |
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| CRBN ligand-762 |
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| CRBN ligand-350 |
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| CRBN ligand-545 |
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| CRBN ligand-311 |
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| CRBN ligand-759 |
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| CRBN ligand-241 |
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| CRBN ligand-654 |
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| Desamino lenalidomide-6-I |
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| CRBN ligand-613 |
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| CRBN ligand-499 |
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| CRBN ligand-664 |
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| Desamino lenalidomide-7-propyne |
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| CRBN ligand-323 |
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| CRBN ligand-462 |
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| CRBN ligand-756 |
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| CRBN ligand-769 |
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| CRBN ligand-254 |
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| CRBN ligand-839 |
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| CRBN ligand-449 |
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| CRBN ligand-572 |
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| CRBN ligand-318 |
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| CRBN ligand-619 |
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|
≥98.0% |
| CRBN ligand-751 |
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| CRBN ligand-421 |
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| CRBN ligand-615 |
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| CRBN ligand-638 |
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| CRBN ligand-422 |
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| CRBN ligand-454 |
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| CRBN ligand-588 |
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| CRBN ligand-643 |
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| CRBN ligand-540 |
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| Hydrouracil-(4-Br-2,6-difluorobenzene) |
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| CRBN ligand-357 |
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| CRBN ligand-336 |
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| CRBN ligand-261 |
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| CRBN ligand-548 |
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| Hydrouracil-(4-CP) |
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| CRBN ligand-239 |
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| CRBN ligand-732 |
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| CRBN ligand-497 |
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| CRBN ligand-404 |
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| CRBN ligand-605 |
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| CRBN ligand-835 |
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| CRBN ligand-821 |
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| CRBN ligand-529 |
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| CRBN ligand-293 |
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| CRBN ligand-602 |
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| CRBN ligand-758 |
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| CRBN ligand-456 |
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| CRBN ligand-442 |
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| CRBN ligand-824 |
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| CRBN ligand-624 |
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| CRBN ligand-321 |
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| CRBN ligand-706 |
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| CRBN ligand-507 |
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| CRBN ligand-607 |
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| CRBN ligand-747 |
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| CRBN ligand-820 |
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| CRBN ligand-255 |
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| CRBN ligand-194 |
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| CRBN ligand-444 |
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| CRBN ligand-697 |
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| CRBN ligand-489 |
|
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| CRBN ligand-337 |
|
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| CRBN ligand-834 |
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| CRBN ligand-551 |
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| CRBN ligand-542 |
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| CRBN ligand-272 |
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| CRBN ligand-674 |
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| CRBN ligand-749 |
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| CRBN ligand-900 |
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| Thalidomide-5-NH2-6-F |
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| CRBN ligand-888 |
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|
99.36% |
| CRBN ligand-452 |
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| CRBN ligand-493 |
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| CRBN ligand-464 |
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| CRBN ligand-549 |
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| CRBN ligand-729 |
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| CRBN ligand-450 |
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| CRBN ligand-663 |
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| CRBN ligand-275 |
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| CRBN ligand-385 |
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| CRBN ligand-648 |
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| CRBN ligand-248 |
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| CRBN ligand-721 |
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| CRBN ligand-270 |
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| CRBN ligand-575 |
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| CRBN ligand-285 |
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| CRBN ligand-681 |
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| CRBN ligand-349 |
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| CRBN ligand-623 |
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| CRBN ligand-381 |
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| CRBN ligand-665 |
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| CRBN ligand-334 |
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| CRBN ligand-790 |
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| CRBN ligand-183 |
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| CRBN ligand-313 |
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| CRBN ligand-301 |
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| CRBN ligand-708 |
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| CRBN ligand-233 |
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| CRBN ligand-709 |
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| CRBN ligand-847 |
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| CRBN ligand-441 |
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| CRBN ligand-483 |
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| CRBN ligand-420 |
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| CRBN ligand-110 |
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| CRBN ligand-514 |
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| CRBN ligand-573 |
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| CRBN ligand-63 |
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| CRBN ligand-792 |
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| CRBN ligand-300 |
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| CRBN ligand-276 |
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| CRBN ligand-707 |
|
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|
99.53% |
| CRBN ligand-396 |
|
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| CRBN ligand-467 |
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| CRBN ligand-451 |
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|
|
| Thalidomide-NH-CH2-COOH TFA |
|
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| CRBN ligand-518 |
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| CRBN ligand-339 |
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| (S,R,S)-AHPC 2-OH hydrochloride |
|
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| CRBN ligand-259 |
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| CRBN ligand-639 |
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| CRBN ligand-685 |
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| CRBN ligand-470 |
|
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|
|
| Desamino lenalidomide-7-CO |
|
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|
|
| 3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione |
|
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| CRBN ligand-506 |
|
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|
| Thalidomide-O-amido-PEG1-azide |
|
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| CRBN ligand-265 |
|
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| CRBN ligand-356 |
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| CRBN ligand-565 |
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| CRBN ligand-434 |
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| CRBN ligand-472 |
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| CRBN ligand-322 |
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| CRBN ligand-672 |
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| CRBN ligand-576 |
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| CRBN ligand-193 |
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| CRBN ligand-281 |
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| CRBN ligand-869 |
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| CRBN ligand-508 |
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| CRBN ligand-426 |
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| CRBN ligand-314 |
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| CRBN ligand-429 |
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| CRBN ligand-164 |
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| CRBN ligand-221 |
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| CRBN ligand-750 |
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| CRBN ligand-207 |
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| CRBN ligand-341 |
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| CRBN ligand-885 |
|
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|
98.10% |
| CRBN ligand-230 |
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| CRBN ligand-559 |
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| CRBN ligand-203 |
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| CRBN ligand-355 |
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| CRBN ligand-335 |
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| CRBN ligand-214 |
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| CRBN ligand-561 |
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| CRBN ligand-411 |
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| CRBN ligand-699 |
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| CRBN ligand-755 |
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| CRBN ligand-816 |
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| CRBN ligand-162 |
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| CRBN ligand-636 |
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| CRBN ligand-571 |
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| CRBN ligand-616 |
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| CRBN ligand-631 |
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| CRBN ligand-209 |
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| CRBN ligand-831 |
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| CRBN ligand-418 |
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| CRBN ligand-695 |
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| CRBN ligand-687 |
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| PROTAC DHFR Degrader-1 |
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| CRBN ligand-614 |
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| CRBN ligand-354 |
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| CRBN ligand-437 |
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| CRBN ligand-845 |
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| CRBN ligand-889 |
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| CRBN ligand-250 |
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| CRBN ligand-380 |
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| CRBN ligand-408 |
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| Thalidomide-5-F-6-I |
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| CRBN ligand-698 |
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| 4-Br-7-O-Desamino lenalidomide |
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| CRBN ligand-712 |
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| CRBN ligand-740 |
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| CRBN ligand-641 |
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| CRBN ligand-481 |
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| CRBN ligand-487 |
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| CRBN ligand-539 |
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| CRBN ligand-558 |
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| CRBN ligand-860 |
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| CRBN ligand-716 |
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| CRBN ligand-494 |
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| CRBN ligand-583 |
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| CRBN ligand-727 |
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| CRBN ligand-291 |
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| CRBN ligand-379 |
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| CRBN ligand-886 |
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| CRBN ligand-388 |
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| CRBN ligand-526 |
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| CRBN ligand-610 |
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| CRBN ligand-258 |
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| CRBN ligand-360 |
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| CRBN ligand-217 |
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| CRBN ligand-347 |
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| CRBN ligand-316 |
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| CRBN ligand-752 |
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| CRBN ligand-362 |
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| CRBN ligand-768 |
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| CRBN ligand-705 |
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| CRBN ligand-353 |
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| CRBN ligand-378 |
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| CRBN ligand-599 |
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| CRBN ligand-595 |
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| CRBN ligand-822 |
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| CRBN ligand-622 |
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| CRBN ligand-647 |
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| CRBN ligand-245 |
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| CRBN ligand-787 |
|
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| CRBN ligand-784 |
|
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| CRBN ligand-859 |
|
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|
|
| Phenyl-glutarimide 4'-oxyacetic acid |
|
|
|
|
|
|
|
|
|
|
|
|
|
98.09% |
| CRBN ligand-720 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| CRBN ligand-210 |
|
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|
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| CRBN ligand-841 |
|
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|
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| CRBN ligand-537 |
|
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|
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| CRBN ligand-365 |
|
|
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|
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| CRBN ligand-693 |
|
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|
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| CRBN ligand-433 |
|
|
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|
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| CRBN ligand-400 |
|
|
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|
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|
|
| CRBN ligand-299 |
|
|
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|
|
| CRBN ligand-306 |
|
|
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|
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| CRBN ligand-890 |
|
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|
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| CRBN ligand-630 |
|
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|
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| CRBN ligand-346 |
|
|
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|
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| CRBN ligand-842 |
|
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| CRBN ligand-736 |
|
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| CRBN ligand-797 |
|
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| CRBN ligand-586 |
|
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|
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| CRBN ligand-793 |
|
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| CRBN ligand-832 |
|
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| CRBN ligand-490 |
|
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| CRBN ligand-829 |
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| CRBN ligand-469 |
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| CRBN ligand-479 |
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| CRBN ligand-457 |
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| CRBN ligand-658 |
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|
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| CRBN ligand-513 |
|
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|
|
| (R,S,R)-AHPC-NHBoc |
|
|
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|
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| CRBN ligand-763 |
|
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|
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| CRBN ligand-236 |
|
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|
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| DCAF1 binder 3 |
|
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|
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| CRBN ligand-854 |
|
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| CRBN ligand-628 |
|
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| CRBN ligand-521 |
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| CRBN ligand-358 |
|
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| CRBN ligand-671 |
|
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|
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| CRBN ligand-439 |
|
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|
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| CRBN ligand-657 |
|
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|
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| CRBN ligand-343 |
|
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|
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| CRBN ligand-536 |
|
|
|
|
|
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|
|
|
|
|
|
|
| (S,R,S)-AHPC-Me-PEG3-azide |
|
|
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|
|
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|
|
| CRBN ligand-701 |
|
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|
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| CRBN ligand-424 |
|
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| CRBN ligand-216 |
|
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| CRBN ligand-683 |
|
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| CRBN ligand-510 |
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| CRBN ligand-696 |
|
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|
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| CRBN ligand-308 |
|
|
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|
|
| Thalidomide-SH |
|
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|
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| CRBN ligand-801 |
|
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| CRBN ligand-412 |
|
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|
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| CRBN ligand-578 |
|
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|
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| CRBN ligand-455 |
|
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|
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| CRBN ligand-392 |
|
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| CRBN ligand-391 |
|
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|
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| CRBN ligand-865 |
|
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|
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| CRBN ligand-213 |
|
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|
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| CRBN ligand-626 |
|
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| CRBN ligand-646 |
|
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| CRBN ligand-651 |
|
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| CRBN ligand-673 |
|
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|
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| CRBN ligand-471 |
|
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|
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| CRBN ligand-794 |
|
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| CRBN ligand-676 |
|
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|
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| CRBN ligand-757 |
|
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|
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| CRBN ligand-535 |
|
|
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|
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|
|
|
|
|
| Desamino lenalidomide-4-F-7-Br |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.90% |
| CRBN ligand-443 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Thalidomide-Piperazine-PEG2-NH2 hydrochloride |
|
|
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|
|
| CRBN ligand-484 |
|
|
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|
|
| (S,S,S)-AHPC |
|
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|
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| CRBN ligand-800 |
|
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|
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| CRBN ligand-488 |
|
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| CRBN ligand-403 |
|
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|
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| CRBN ligand-795 |
|
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|
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| CRBN ligand-741 |
|
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|
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| CRBN ligand-307 |
|
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|
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| CRBN ligand-45 |
|
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|
|
| CRBN ligand-818 |
|
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|
|
| Thalidomide-5-methanol |
|
|
|
|
|
|
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|
|
| CRBN ligand-796 |
|
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|
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| CRBN ligand-589 |
|
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|
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| CRBN ligand-229 |
|
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|
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| CRBN ligand-858 |
|
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|
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| CRBN ligand-242 |
|
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|
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| CRBN ligand-644 |
|
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|
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| CRBN ligand-718 |
|
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|
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| CRBN ligand-295 |
|
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|
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| CRBN ligand-290 |
|
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|
|
| SJ6145 |
|
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|
|
| CRBN ligand-629 |
|
|
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|
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| CRBN ligand-783 |
|
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|
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| CRBN ligand-637 |
|
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|
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| CRBN ligand-386 |
|
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|
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| CRBN ligand-689 |
|
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|
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| CRBN ligand-849 |
|
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|
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| CRBN ligand-863 |
|
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|
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| CRBN ligand-875 |
|
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| CRBN ligand-112 |
|
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| CRBN ligand-482 |
|
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|
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| CRBN ligand-466 |
|
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|
|
| CC-17369 hydrochloride |
|
|
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|
|
| CRBN ligand-74 |
|
|
|
|
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|
|
|
|
|
|
| Desamino lenalidomide-4-Br-5-F |
|
|
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|
|
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|
|
| CRBN ligand-568 |
|
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|
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| CRBN ligand-833 |
|
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|
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| CRBN ligand-375 |
|
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|
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| CRBN ligand-811 |
|
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|
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| CRBN ligand-16 |
|
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|
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| CRBN ligand-427 |
|
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| CRBN ligand-283 |
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| CRBN ligand-653 |
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| CRBN ligand-84 |
|
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|
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| CRBN ligand-574 |
|
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| CRBN ligand-352 |
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| CRBN ligand-662 |
|
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| CRBN ligand-627 |
|
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| CRBN ligand-440 |
|
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| CRBN ligand-543 |
|
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| CRBN ligand-717 |
|
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|
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| CRBN ligand-780 |
|
|
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|
|
|
|
| Hydrouracil-4-benzazimide-7-NH2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Desamino lenalidomide-5-acetonitrile |
|
|
|
|
|
|
|
|
|
|
|
|
|
99.56% |
| CRBN ligand-345 |
|
|
|
|
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|
|
|
| CRBN ligand-231 |
|
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| CRBN ligand-461 |
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| CRBN ligand-303 |
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| CRBN ligand-563 |
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| CRBN ligand-852 |
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| CRBN ligand-587 |
|
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| CRBN ligand-805 |
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| CRBN ligand-201 |
|
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| CRBN ligand-635 |
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| CRBN ligand-713 |
|
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| CRBN ligand-799 |
|
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| CRBN ligand-825 |
|
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| CRBN ligand-373 |
|
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| CRBN ligand-633 |
|
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| CRBN ligand-580 |
|
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|
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| CRBN ligand-296 |
|
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| CRBN ligand-393 |
|
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|
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| CRBN ligand-555 |
|
|
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|
|
|
| Thalidomide-4-OH-(S)-CH3 |
|
|
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|
|
| CRBN ligand-528 |
|
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|
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| CRBN ligand-413 |
|
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|
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| CRBN ligand-264 |
|
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|
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| CRBN ligand-271 |
|
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| CRBN ligand-659 |
|
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| CRBN ligand-330 |
|
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|
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| CRBN ligand-779 |
|
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| CRBN ligand-634 |
|
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| CRBN ligand-234 |
|
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| CRBN ligand-813 |
|
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| CRBN ligand-861 |
|
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|
|
| CRBN ligand-465 |
|
|
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|
|
|
| CG 858-Neg |
|
|
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|
|
| CRBN ligand-772 |
|
|
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| CRBN ligand-815 |
|
|
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|
|
| CRBN ligand-566 |
|
|
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| E3 ligase Ligand 30 |
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| CRBN ligand-491 |
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| CRBN ligand-581 |
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| CRBN ligand-235 |
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| CRBN ligand-857 |
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| CRBN ligand-320 |
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| CRBN ligand-240 |
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| CRBN ligand-830 |
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| CRBN ligand-406 |
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| CRBN ligand-286 |
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| CRBN ligand-274 |
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| CRBN ligand-417 |
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| CRBN ligand-608 |
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| CRBN ligand-609 |
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| CRBN ligand-218 |
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| CRBN ligand-262 |
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| CRBN ligand-596 |
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| CRBN ligand-682 |
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| CRBN ligand-722 |
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| CRBN ligand-711 |
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| CRBN ligand-243 |
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| CRBN ligand-525 |
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| CRBN ligand-263 |
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| CRBN ligand-288 |
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| CRBN ligand-238 |
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| CRBN ligand-810 |
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| CRBN ligand-503 |
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| CRBN ligand-649 |
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| CRBN ligand-302 |
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| CRBN ligand-251 |
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| CRBN ligand-368 |
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| CRBN ligand-531 |
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| CRBN ligand-887 |
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| Hydrouracil-(4-Chlorophenoxy)-O-C-COOH |
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| CRBN ligand-414 |
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| CRBN ligand-719 |
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| CRBN ligand-553 |
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| Desamino lenalidomide-4-Br-7-OH |
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| CRBN ligand-670 |
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| CRBN ligand-567 |
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| CRBN ligand-823 |
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| (S)-Thalidomide-5-OH |
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| CRBN ligand-601 |
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| CRBN ligand-593 |
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| CRBN ligand-851 |
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| CRBN ligand-846 |
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| (S,R,S)-AHPC-PEG5-Azide |
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| CRBN ligand-642 |
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| CRBN ligand-398 |
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| CRBN ligand-438 |
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| CRBN ligand-405 |
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| CRBN ligand-560 |
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| CRBN ligand-778 |
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| CRBN ligand-677 |
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| Benzothiazole-CH2(NH-CO-CH2Cl)-CONH-CH2-Ph |
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| CRBN ligand-879 |
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| CRBN ligand-215 |
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| CRBN ligand-748 |
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| CRBN ligand-502 |
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| CRBN ligand-384 |
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| CRBN ligand-530 |
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| CRBN ligand-476 |
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| CRBN ligand-237 |
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| CRBN ligand-585 |
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| CRBN ligand-524 |
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| CRBN ligand-703 |
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| CRBN ligand-459 |
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| CRBN ligand-419 |
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| CRBN ligand-463 |
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| CRBN ligand-370 |
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| CRBN ligand-219 |
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| CRBN ligand-848 |
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| CRBN ligand-331 |
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| (S,R,S)-AHPC(Me)-amido-C2-acid |
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| CRBN ligand-196 |
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| CRBN ligand-777 |
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| CRBN ligand-764 |
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| CRBN ligand-509 |
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| CRBN ligand-416 |
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| CRBN ligand-266 |
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| CRBN ligand-305 |
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| CRBN ligand-597 |
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| CRBN ligand-361 |
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| CRBN ligand-844 |
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| CRBN ligand-612 |
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| CRBN ligand-278 |
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| CRBN ligand-564 |
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| Hydrouracil-4-Iodophenyl |
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| CRBN ligand-446 |
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| CRBN ligand-402 |
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| CRBN ligand-655 |
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| 4-Me-Thalidomide |
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|
98.0% |
| CRBN ligand-226 |
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| CRBN ligand-533 |
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| CRBN ligand-83 |
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| CRBN ligand-591 |
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| CRBN ligand-340 |
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| CRBN ligand-399 |
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| CRBN ligand-279 |
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| CRBN ligand-534 |
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| CRBN ligand-791 |
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| CRBN ligand-372 |
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| CRBN ligand-317 |
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| CRBN ligand-603 |
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| CRBN ligand-468 |
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| CRBN ligand-739 |
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| CRBN ligand-222 |
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|
99.96% |
| CRBN ligand-309 |
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| NH2-MeO-Ph-amide-(2,6-Dioxo-3-Pip) |
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| Desamino lenalidomide-4-COOH |
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| CRBN ligand-700 |
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| CRBN ligand-837 |
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| CRBN ligand-432 |
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| Desamino lenalidomide-4-acetonitrile |
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| CRBN ligand-415 |
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| Thalidomide-O-PNB ester |
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| CRBN ligand-866 |
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| CRBN ligand-738 |
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| CRBN ligand-776 |
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| CRBN ligand-812 |
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| CRBN ligand-598 |
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| CRBN ligand-324 |
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| CRBN ligand-277 |
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| CRBN ligand-326 |
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| CRBN ligand-367 |
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| CRBN ligand-856 |
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| CRBN ligand-505 |
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| CRBN ligand-410 |
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| CRBN ligand-532 |
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| CRBN ligand-754 |
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| CRBN ligand-249 |
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| CRBN ligand-520 |
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| CRBN ligand-401 |
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| CRBN ligand-785 |
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| CRBN ligand-329 |
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| CRBN ligand-445 |
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| CRBN ligand-621 |
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| C5 Lenalidomide-6-fluoro |
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| CRBN ligand-425 |
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| CRBN ligand-517 |
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| CRBN ligand-828 |
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| CRBN ligand-765 |
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| Thalidomide-O-amido-PEG3-azide |
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| CRBN ligand-808 |
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| CRBN ligand-269 |
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| CRBN ligand-766 |
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|
|
| Desamino lenalidomide-cyano |
|
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|
99.91% |
| CRBN ligand-843 |
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| CRBN ligand-523 |
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| CRBN ligand-541 |
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| CRBN ligand-327 |
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| CRBN ligand-431 |
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| CRBN ligand-516 |
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| CRBN ligand-582 |
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|
|
| 7-F-4-I-Desamino lenalidomide |
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| CRBN ligand-715 |
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| CRBN ligand-666 |
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| CRBN ligand-390 |
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| CRBN ligand-282 |
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| CRBN ligand-486 |
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| CRBN ligand-827 |
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| CRBN ligand-611 |
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| CRBN ligand-656 |
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| CRBN ligand-247 |
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| CRBN ligand-773 |
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| CRBN ligand-473 |
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| CRBN ligand-688 |
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| CRBN ligand-492 |
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| CRBN ligand-742 |
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| CRBN ligand-853 |
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| CRBN ligand-252 |
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| CRBN ligand-268 |
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| CRBN ligand-409 |
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| CRBN ligand-546 |
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| CRBN ligand-199 |
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| CRBN ligand-678 |
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| CRBN ligand-496 |
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| CRBN ligand-806 |
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| CRBN ligand-460 |
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| CRBN ligand-280 |
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| CRBN ligand-904 |
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| CRBN ligand-871 |
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| CRBN ligand-312 |
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| CRBN ligand-594 |
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| CRBN ligand-817 |
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| CRBN ligand-338 |
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| CRBN ligand-407 |
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| CRBN ligand-632 |
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| CRBN ligand-724 |
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| CRBN ligand-310 |
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| CRBN ligand-315 |
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| CRBN ligand-246 |
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| CRBN ligand-319 |
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| CRBN ligand-227 |
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| CRBN ligand-679 |
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| CRBN ligand-387 |
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| CRBN ligand-743 |
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| 5-Fluoro-pomalidomide |
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| CRBN ligand-771 |
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| CRBN ligand-198 |
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| CRBN ligand-725 |
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| CRBN ligand-527 |
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| CRBN ligand-577 |
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| Desamino lenalidomide-ethynyl |
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| Thalidomide-4-F,5-Br |
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99.37% |
| CRBN ligand-383 |
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| VHL Ligand intermediate-1 |
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| CRBN ligand-205 |
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| CRBN ligand-731 |
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| CRBN ligand-710 |
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| CRBN ligand-745 |
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| CRBN ligand-297 |
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| Desamino lenalidomide-5-F-4-CH2NH2 hydrochloride |
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| CRBN ligand-435 |
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| CRBN ligand-294 |
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| CRBN ligand-668 |
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| CRBN ligand-819 |
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| CRBN ligand-669 |
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| CRBN ligand-802 |
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| CRBN ligand-814 |
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| CRBN ligand-692 |
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| CRBN ligand-737 |
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| CRBN ligand-364 |
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| Desamino lenalidomide-4-Br-6-acetonitrile |
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| CRBN ligand-809 |
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| CRBN ligand-640 |
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| CRBN ligand-257 |
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| CRBN ligand-344 |
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| CRBN ligand-770 |
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| CRBN ligand-342 |
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| CRBN ligand-562 |
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| CRBN ligand-862 |
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| CRBN ligand-374 |
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| CRBN ligand-684 |
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| CRBN ligand-485 |
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| CRBN ligand-850 |
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| CRBN ligand-108 |
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| CRBN ligand-760 |
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| CRBN ligand-480 |
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| CRBN ligand-260 |
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| (S,R,S)-AHPC-amide-C10-azide |
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| CRBN ligand-870 |
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| CRBN ligand-550 |
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| CRBN ligand-767 |
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| CRBN ligand-569 |
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| CRBN ligand-287 |
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| Thalidomide-5-piperazine |
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| CRBN ligand-232 |
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| (R,R,S)-AHPC |
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| CRBN ligand-212 |
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| CRBN ligand-667 |
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| CRBN ligand-292 |
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| CRBN ligand-475 |
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| CRBN ligand-691 |
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| CRBN ligand-501 |
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| CRBN ligand-584 |
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| Bis-PEG2-amine-Thalidomidehydrochloride |
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